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dltA protein (Staphylococcus xylosus) - STRING interaction network
"dltA" - D-alanine--D-alanyl carrier protein ligase in Staphylococcus xylosus
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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dltAD-alanine--D-alanyl carrier protein ligase; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall; Belongs to the AT [...] (487 aa)    
Predicted Functional Partners:
AID43273.1
annotation not available (404 aa)
 
   
  0.999
dltC
D-alanyl carrier protein; Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall (78 aa)
 
 
  0.999
AID43271.1
annotation not available (382 aa)
 
   
  0.997
ddl
D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family (356 aa)
         
  0.908
AID42820.1
Alanine racemase; Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids; Belongs to the alanine racemase family (357 aa)
       
  0.906
AID42483.1
D-alanine aminotransferase; Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction (281 aa)
       
    0.900
AID43275.1
D-alanyl-lipoteichoic acid biosynthesis protein; FIG01108580 (48 aa)
              0.821
AID43607.1
annotation not available (428 aa)
 
          0.782
rpmH
annotation not available (45 aa)
           
  0.569
AID43836.1
annotation not available (172 aa)
 
 
 
  0.548
Your Current Organism:
Staphylococcus xylosus
NCBI taxonomy Id: 1288
Other names: ATCC 29971, CCUG 7324, CIP 81.66, DSM 20266, HAMBI 2057, JCM 2418, NCTC 11043, NRRL B-14776, S. xylosus, Staphylococcus xylosus
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