STRINGSTRING
gcvH protein (Staphylococcus xylosus) - STRING interaction network
"gcvH" - Glycine cleavage system H protein in Staphylococcus xylosus
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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gcvHGlycine cleavage system H protein; Is also involved in protein lipoylation via its role as an octanoyl/lipoyl carrier protein intermediate; Belongs to the GcvH family (126 aa)    
Predicted Functional Partners:
gcvT
Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine (363 aa)
  0.998
gcvPB
Probable glycine dehydrogenase (decarboxylating) subunit 2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily (492 aa)
  0.995
gcvPA
Probable glycine dehydrogenase (decarboxylating) subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein (450 aa)
  0.994
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (412 aa)
   
 
  0.942
AID42705.1
annotation not available (473 aa)
 
 
  0.906
AID43127.1
annotation not available (468 aa)
 
 
  0.898
rocA
annotation not available (514 aa)
     
 
  0.803
lipM
Octanoyltransferase LipM; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (276 aa)
 
 
  0.797
lipL
Octanoyl-[GcvH]-protein N-octanoyltransferase; Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes; Belongs to the octanoyltransferase LipL family (278 aa)
   
 
  0.713
AID43300.1
annotation not available (99 aa)
   
      0.706
Your Current Organism:
Staphylococcus xylosus
NCBI taxonomy Id: 1288
Other names: ATCC 29971, CCUG 7324, CIP 81.66, DSM 20266, HAMBI 2057, JCM 2418, NCTC 11043, NRRL B-14776, S. xylosus, Staphylococcus xylosus
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