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pdxS protein (Staphylococcus xylosus) - STRING interaction network
"pdxS" - Pyridoxal 5'-phosphate synthase subunit PdxS in Staphylococcus xylosus
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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pdxSPyridoxal 5’-phosphate synthase subunit PdxS; Catalyzes the formation of pyridoxal 5’-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively; Belongs to the PdxS/SNZ family (295 aa)    
Predicted Functional Partners:
pdxT
Pyridoxal 5’-phosphate synthase subunit PdxT; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5’-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS (193 aa)
  0.999
AID43549.1
annotation not available (276 aa)
       
  0.907
AID43678.1
annotation not available (457 aa)
 
     
  0.739
guaA
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP (513 aa)
   
   
  0.674
guaB
Inosine-5’-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5’-phosphate (IMP) to xanthosine 5’-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth; Belongs to the IMPDH/GMPR family (488 aa)
   
        0.522
AID42465.1
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5’-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5’-phosphate; In the C-terminal section; belongs to the HTP reductase family (347 aa)
         
  0.505
AID41606.1
annotation not available (282 aa)
           
  0.485
AID43449.1
Aspartate aminotransferase (475 aa)
         
  0.471
AID42540.1
annotation not available (372 aa)
           
  0.470
panD
Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (128 aa)
           
  0.469
Your Current Organism:
Staphylococcus xylosus
NCBI taxonomy Id: 1288
Other names: ATCC 29971, CCUG 7324, CIP 81.66, DSM 20266, HAMBI 2057, JCM 2418, NCTC 11043, NRRL B-14776, S. xylosus, Staphylococcus xylosus
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