STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRO17159.1Hypothetical protein. (619 aa)    
Predicted Functional Partners:
KRO16475.1
Potassium uptake protein ktrB.
  
 
 0.927
KRO15516.1
NADPH dehydrogenase.
  
 
 0.778
cinA
Competence damage-inducible protein A; Belongs to the CinA family.
    
 0.755
KRO17158.1
Prolyl aminopeptidase; Releases the N-terminal proline from various substrates. Belongs to the peptidase S33 family.
     
 0.693
KRO16608.1
Voltage gated chloride channel family protein.
     
 0.690
KRO18587.1
tRNA and rRNA cytosine-C5-methytransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
  
   0.654
guaB
IMP dehydrogenase GMP reductase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
     
 0.646
KRO17117.1
Heavy metal translocating P-type ATPase.
  
  
 0.604
KRO17950.1
Small-conductance mechanosensitive channel protein.
 
   
 0.564
dnaJ
DnaJ-like molecular chaperone; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between [...]
   
 
 0.561
Your Current Organism:
Lactobacillus saniviri
NCBI taxonomy Id: 1293598
Other names: L. saniviri JCM 17471 = DSM 24301, Lactobacillus saniviri DSM 24301, Lactobacillus saniviri DSM 24301 = JCM 17471, Lactobacillus saniviri JCM 17471, Lactobacillus saniviri JCM 17471 = DSM 24301, Lactobacillus saniviri YIT 12363, Lactobacillus sp. YIT 12363
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.