STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
J056_0013183-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (450 aa)    
Predicted Functional Partners:
J056_002244
3-hydroxy-3-methylglutaryl coenzyme A reductase.
  
 
 0.999
J056_000234
Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.997
J056_004479
3-ketoacyl-CoA thiolase B, peroxisomal; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.994
J056_003284
Uncharacterized protein.
  
 0.945
J056_003278
Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.
    
 0.944
J056_001735
Lanosterol 14-alpha demethylase; Belongs to the cytochrome P450 family.
  
 
 0.943
J056_000439
Squalene monooxygenase.
   
  
 0.922
J056_001663
Squalene synthase.
   
 
 0.912
J056_002981
Uncharacterized protein.
     
 0.905
J056_002041
Methylsterol monooxygenase; Belongs to the sterol desaturase family.
   
 
 0.901
Your Current Organism:
Wallemia ichthyophaga
NCBI taxonomy Id: 1299270
Other names: W. ichthyophaga EXF-994, Wallemia ichthyophaga EXF-994
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