STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EOD00736.1Pyruvate carboxyl transferase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1143 aa)    
Predicted Functional Partners:
birA
Biotin-protein ligase/ Biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
 
 0.994
EOD01128.1
Carboxyl transferase.
 
 0.991
EOD00853.1
Pyruvate kinase; Belongs to the pyruvate kinase family.
   
 0.958
EOD00739.1
Hypothetical protein.
  
 
 0.958
EOD00424.1
Pyruvate-flavodoxin oxidoreductase.
    
 0.951
EOC99576.1
Pyruvate-flavodoxin oxidoreductase.
    
 0.951
EOD00985.1
Biotin carboxyl carrier protein of acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
  
 
 0.943
EOD01559.1
Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
  
 
 0.939
EOC99250.1
Alcohol dehydrogenase, Acetaldehyde dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
   
 0.939
EOD00316.1
NADP-dependent malic enzyme.
   
 0.938
Your Current Organism:
Caldisalinibacter kiritimatiensis
NCBI taxonomy Id: 1304284
Other names: C. kiritimatiensis, Caldisalinibacter kiritimatiensis Ben Hania et al. 2015, Clostridiaceae bacterium L21-TH-D2, DSM 26826, JCM 18664, strain L21-TH-D2
Server load: low (24%) [HD]