STRINGSTRING
polC protein (Streptococcus pyogenes) - STRING interaction network
"polC" - DNA polymerase III PolC-type in Streptococcus pyogenes
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
polCDNA polymerase III PolC-type; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3’ to 5’ exonuclease activity (1465 aa)    
Predicted Functional Partners:
polA
annotation not available (880 aa)
     
  0.982
dnaN
annotation not available (378 aa)
     
  0.974
holA
annotation not available (346 aa)
       
  0.965
holB
annotation not available (291 aa)
       
  0.959
AIW24953.1
annotation not available (561 aa)
       
  0.934
pyk
annotation not available (500 aa)
       
  0.904
AIW24502.1
annotation not available (58 aa)
         
    0.900
dnaC
Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity (453 aa)
         
  0.893
dnaE
DNA polymerase III subunit alpha; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3’ to 5’ exonuclease activity. The alpha chain is the DNA polymerase (By similarity); Belongs to the DNA polymerase type-C family. DnaE subfamily (1036 aa)
   
 
0.887
dnaG
annotation not available (604 aa)
         
  0.880
Your Current Organism:
Streptococcus pyogenes
NCBI taxonomy Id: 1314
Other names: ATCC 12344, CCUG 12701, CCUG 4207, CIP 56.41, DSM 20565, JCM 5674, LMG 14700, Micrococcus scarlatinae, NCAIM B.01705, NCTC 8198, S. pyogenes, Streptococcus erysipelatos, Streptococcus hemolyticus, Streptococcus pyogenes, Streptococcus scarlatinae
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