STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
srtBSortase; Derived by automated computational analysis using gene prediction method: Protein Homology. (241 aa)    
Predicted Functional Partners:
isdE
ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.942
srtA_1
Sortase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.903
SrtE
Lantibiotic ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.866
srtA
Lantibiotic streptin; Lanthionine-containing peptide antibiotic (lantibiotic) active on certain Gram-positive bacteria. The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous transmembrane pores.
      
 0.863
srtF
Lantibiotic ABC transporter ATP-binding protein; Implicated in the export process of the lantibiotic SrtA.
      
 0.863
lepB
Signal peptidase I; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.841
AKZ49684.1
Fibronectin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.763
AKZ51341.1
Fimbrial protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
   0.736
SrtG
Lantibiotic ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.678
AKZ49682.1
Fibronectin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.668
Your Current Organism:
Streptococcus pyogenes
NCBI taxonomy Id: 1314
Other names: ATCC 12344, CCUG 12701, CCUG 4207, CIP 56.41, DSM 20565, JCM 5674, LMG 14700, LMG:14700, Micrococcus scarlatinae, NCAIM B.01705, NCTC 8198, S. pyogenes, Streptococcus erysipelatos, Streptococcus hemolyticus, Streptococcus scarlatinae
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