STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W1PWX0_AMBTCPeroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (200 aa)    
Predicted Functional Partners:
W1P216_AMBTC
Thioredoxin domain-containing protein.
   
 0.837
U5CSE5_AMBTC
Thioredoxin domain-containing protein.
   
 0.830
W1PLV7_AMBTC
Thioredoxin domain-containing protein.
    
 0.740
W1PW25_AMBTC
Thioredoxin domain-containing protein.
   
 0.714
U5DA85_AMBTC
Ubiquitin-related modifier 1 homolog; Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins. The thiocarboxylated form serves as substrate for conjugation and oxidative stress spec [...]
   
 
 0.684
W1NSZ2_AMBTC
Thioredoxin reductase.
  
 0.684
W1PSJ1_AMBTC
Uncharacterized protein.
    
 0.672
W1NUQ4_AMBTC
Thioredoxin domain-containing protein.
   
 0.670
W1P0A1_AMBTC
Thioredoxin domain-containing protein.
   
 0.670
W1P1I3_AMBTC
Uncharacterized protein.
    
 0.670
Your Current Organism:
Amborella trichopoda
NCBI taxonomy Id: 13333
Other names: A. trichopoda, Amborella trichopoda Baill.
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.