STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAC1Nuclear distribution protein PAC1; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs. (393 aa)    
Predicted Functional Partners:
AOL_s00006g370
Uncharacterized protein.
    
 0.995
AOL_s00043g622
NUDE_C domain-containing protein.
    
 
 0.961
AOL_s00078g451
CS domain-containing protein.
    
 0.945
AOL_s00078g214
Uncharacterized protein.
   
 0.937
AOL_s00078g61
Uncharacterized protein.
    
 0.923
AOL_s00081g159
CAP-Gly domain-containing protein.
    
 0.912
AOL_s00193g79
Dynein light chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures.
    
 0.899
AOL_s00112g27
Uncharacterized protein.
   
 0.844
AOL_s00210g115
SGNH_hydro domain-containing protein.
    
 0.839
AOL_s00078g557
Uncharacterized protein.
     
 0.796
Your Current Organism:
Arthrobotrys oligospora
NCBI taxonomy Id: 756982
Other names: A. oligospora ATCC 24927, Arthrobotrys oligospora ATCC 24927
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