STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_2380Nuclease. (137 aa)    
Predicted Functional Partners:
ACPL_2381
Hypothetical protein.
       0.631
rnpA
Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
   
    0.593
ACPL_8141
Membrane proteins related to metalloendopeptidases.
  
     0.543
plb1
Phospholipase B1, membrane-associated.
 
     0.540
ACPL_2115
Putative metalloprotease; Membrane proteins related to metalloendopeptidases.
  
     0.518
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
   
 
 0.518
ACPL_333
Glycyl-glycine endopeptidase ALE-1; Membrane proteins related to metalloendopeptidases.
  
     0.510
gltB
Glutamate synthase domain 2.
     
 0.456
ACPL_5732
Putative peptidoglycan O-acetyltransferase yrhL; Predicted acyltransferases.
  
  
 0.439
ACPL_5678
Hypothetical protein; Sterol desaturase.
   
    0.431
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.