STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nrmNurim; Putative protein-S-isoprenylcysteine methyltransferase. (228 aa)    
Predicted Functional Partners:
ACPL_6636
Selenium-binding protein 1.
    
  0.901
metH
5-methyltetrahydrofolate-homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
  0.808
sseA
Rhodanese-related sulfurtransferase.
    
  0.806
tst
Rhodanese domain protein; Rhodanese-related sulfurtransferase.
    
  0.806
ACPL_7976
Rhodanese-related sulfurtransferase.
    
  0.806
cysM-2
Cystathionine beta-synthase; Cysteine synthase.
    
  0.801
ACPL_952
Cystathionine beta-synthase; Cysteine synthase.
    
  0.801
megL
Methionine-gamma-lyase; Cystathionine beta-lyases/cystathionine gamma-synthases.
     
  0.800
ACPL_364
Aminotransferase; Aspartate/tyrosine/aromatic aminotransferase.
     
  0.800
sahH
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
     
  0.800
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.