STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
proCHypothetical protein; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (270 aa)    
Predicted Functional Partners:
DT23_16305
Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
 
 0.921
DT23_17700
Hypothetical protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.
   
 0.904
proA
Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
 
 
 0.872
DT23_02445
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 
  0.832
DT23_02450
tRNA-binding protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.816
DT23_14125
Alanine racemase; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
  
 0.755
DT23_05590
Ornithine cyclodeaminase; Catalyzes the formation of L-proline from L-ornithine; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
   
 
 0.750
DT23_02460
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.749
DT23_00595
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
   
 
 0.744
DT23_02440
3-oxoacyl-ACP synthase; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.639
Your Current Organism:
Thioclava indica
NCBI taxonomy Id: 1353528
Other names: Albirhodobacter sp. MCCC 1A00513, KCTC 33533, LMG 27698, LMG:27698, MCCC 1A00513, T. indica, Thioclava indica Liu et al. 2015, Thioclava sp. DT23-4, Thioclava sp. MCCC 1A00513, strain DT23-4
Server load: low (24%) [HD]