STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TBC1D8BTBC1 domain family member 8B. (1197 aa)    
Predicted Functional Partners:
GAK
Cyclin G associated kinase.
   
 
 0.914
DNAJC6
DnaJ heat shock protein family (Hsp40) member C6.
   
 
  0.657
ANKFY1
Ankyrin repeat and FYVE domain containing 1.
   
 
 0.645
CDC16
Cell division cycle 16.
      
 0.548
GAPVD1
GTPase activating protein and VPS9 domains 1.
   
 
 0.489
YIPF6
Protein YIPF.
   
 
  0.485
IGF2R
Insulin like growth factor 2 receptor.
   
 
  0.474
SORT1
Sortilin.
    
  0.470
SNAPIN
SNARE-associated protein Snapin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling; Belongs to t [...]
     
 0.470
TBC1D25
TBC1 domain family member 25.
   
  
 0.466
Your Current Organism:
Monodelphis domestica
NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.