STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IRF6Interferon regulatory factor 6 (494 aa)    
Predicted Functional Partners:
GRHL3
Grainyhead-like 3 (Drosophila)
   
  
 0.707
RIPK4
Receptor-interacting serine-threonine kinase 4
   
 
 0.697
MSX1
Msh homeobox 1
   
  
 0.668
IRX6
Iroquois homeobox 6
      
 0.616
IFITM10
Interferon induced transmembrane protein 10
      
 0.615
TP63
Tumor protein p63; Belongs to the p53 family
   
  
 0.582
CHUK
Conserved helix-loop-helix ubiquitous kinase
    
 
 0.576
TGFB3
Transforming growth factor, beta 3
      
 0.561
UCHL1
Ubiquitin carboxyl-terminal hydrolase isozyme L1; Ubiquitin-protein hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. Also binds to free monoubiquitin and may prevent its degradation in lysosomes. The homodimer may have ATP-independent ubiquitin ligase activity (By similarity); Belongs to the peptidase C12 family
      
 0.555
NHLH1
Nescient helix loop helix 1
      
 0.501
Your Current Organism:
Monodelphis domestica
NCBI taxonomy Id: 13616
Other names: M. domestica, Monodelphis domestica, gray short-tailed opossum
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