STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IRF6Interferon regulatory factor 6. (494 aa)    
Predicted Functional Partners:
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.625
MAVS
CARD_2 domain-containing protein.
    
 0.495
STING1
Transmembrane protein 173.
   
 0.473
IRAK1
Interleukin 1 receptor associated kinase 1.
   
 0.469
RIPK4
Receptor interacting serine/threonine kinase 4.
   
 0.464
CD4
CD4.
   
 
 0.448
TLR4
Toll like receptor 4; Belongs to the Toll-like receptor family.
   
 
 0.437
TNIP1
TNFAIP3 interacting protein 1.
  
   
 0.434
IFNGR1
Fibronectin type-III domain-containing protein.
   
  
 0.429
IKBKE
Inhibitor of nuclear factor kappa B kinase subunit epsilon.
   
 0.418
Your Current Organism:
Monodelphis domestica
NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.