node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ATXN7 | MED12L | ENSMODP00000042740 | ENSMODP00000026599 | SCA7 domain-containing protein. | Mediator complex subunit 12L. | 0.729 |
ATXN7 | PAXIP1 | ENSMODP00000042740 | ENSMODP00000040133 | SCA7 domain-containing protein. | PAX interacting protein 1. | 0.723 |
ATXN7 | RUNX1 | ENSMODP00000042740 | ENSMODP00000026321 | SCA7 domain-containing protein. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.405 |
ATXN7 | RUNX2 | ENSMODP00000042740 | ENSMODP00000058316 | SCA7 domain-containing protein. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.405 |
ATXN7 | RUNX3 | ENSMODP00000042740 | ENSMODP00000045293 | SCA7 domain-containing protein. | Runt domain-containing protein. | 0.405 |
ATXN7 | TBP | ENSMODP00000042740 | ENSMODP00000006780 | SCA7 domain-containing protein. | TATA-box binding protein. | 0.547 |
ATXN7 | ZFHX3 | ENSMODP00000042740 | ENSMODP00000053348 | SCA7 domain-containing protein. | Zinc finger homeobox 3. | 0.541 |
CUX2 | ZFHX3 | ENSMODP00000015346 | ENSMODP00000053348 | Homeobox protein cut-like. | Zinc finger homeobox 3. | 0.546 |
KAT14 | ZFHX3 | ENSMODP00000006860 | ENSMODP00000053348 | Lysine acetyltransferase 14. | Zinc finger homeobox 3. | 0.544 |
MED12L | ATXN7 | ENSMODP00000026599 | ENSMODP00000042740 | Mediator complex subunit 12L. | SCA7 domain-containing protein. | 0.729 |
MED12L | PAXIP1 | ENSMODP00000026599 | ENSMODP00000040133 | Mediator complex subunit 12L. | PAX interacting protein 1. | 0.753 |
MED12L | RUNX1 | ENSMODP00000026599 | ENSMODP00000026321 | Mediator complex subunit 12L. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.405 |
MED12L | RUNX2 | ENSMODP00000026599 | ENSMODP00000058316 | Mediator complex subunit 12L. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.405 |
MED12L | RUNX3 | ENSMODP00000026599 | ENSMODP00000045293 | Mediator complex subunit 12L. | Runt domain-containing protein. | 0.405 |
MED12L | TBP | ENSMODP00000026599 | ENSMODP00000006780 | Mediator complex subunit 12L. | TATA-box binding protein. | 0.459 |
MED12L | ZFHX3 | ENSMODP00000026599 | ENSMODP00000053348 | Mediator complex subunit 12L. | Zinc finger homeobox 3. | 0.723 |
PAXIP1 | ATXN7 | ENSMODP00000040133 | ENSMODP00000042740 | PAX interacting protein 1. | SCA7 domain-containing protein. | 0.723 |
PAXIP1 | MED12L | ENSMODP00000040133 | ENSMODP00000026599 | PAX interacting protein 1. | Mediator complex subunit 12L. | 0.753 |
PAXIP1 | RUNX1 | ENSMODP00000040133 | ENSMODP00000026321 | PAX interacting protein 1. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.403 |
PAXIP1 | RUNX2 | ENSMODP00000040133 | ENSMODP00000058316 | PAX interacting protein 1. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.403 |