STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
UNC5BUnc-5 netrin receptor B. (865 aa)    
Predicted Functional Partners:
NEO1
Neogenin 1.
    
 0.741
NTN3
Netrin 3.
    
 0.703
FLRT3
Fibronectin leucine rich transmembrane protein 3.
    
 0.689
NTN4
Netrin 4.
      
 0.615
ROBO4
Roundabout guidance receptor 4.
     
 0.605
DCC
DCC netrin 1 receptor.
    
 0.601
RGMA
Repulsive guidance molecule BMP co-receptor a.
      
 0.584
DAPK1
Death associated protein kinase 1.
    
 0.524
DLL4
Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.
    
 0.487
DRAXIN
Draxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway.
   
  
 0.484
Your Current Organism:
Monodelphis domestica
NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.