STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NSMAFNeutral sphingomyelinase activation associated factor. (942 aa)    
Predicted Functional Partners:
TNFRSF1A
Uncharacterized protein.
    
 0.986
RACK1
Receptor for activated C kinase 1.
    
0.717
TNF
Tumor necrosis factor; Belongs to the tumor necrosis factor family.
   
 
 0.639
PSMB3
Proteasome subunit beta.
    
 
 0.614
PLEKHG6
Pleckstrin homology and RhoGEF domain containing G6.
    
 0.585
PLEKHG5
Pleckstrin homology and RhoGEF domain containing G5.
    
 0.585
UBXN2B
UBX domain protein 2B.
    
 
 0.543
FAM110B
Family with sequence similarity 110 member B.
      
 0.540
PSMB6
Proteasome subunit beta.
      
 0.459
PSMB4
Proteasome subunit beta; Belongs to the peptidase T1B family.
      
 0.454
Your Current Organism:
Monodelphis domestica
NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.