node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CGA | FSHR | ENSMODP00000056565 | ENSMODP00000001525 | Glycoprotein hormones alpha chain; Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH and follitropin/follicle stimulating hormone/FSH. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways. | Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. | 0.973 |
CGA | LHB | ENSMODP00000056565 | ENSMODP00000017212 | Glycoprotein hormones alpha chain; Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH and follitropin/follicle stimulating hormone/FSH. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways. | Lutropin subunit beta; Promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. | 0.995 |
CGA | LHCGR | ENSMODP00000056565 | ENSMODP00000001486 | Glycoprotein hormones alpha chain; Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH and follitropin/follicle stimulating hormone/FSH. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways. | Lutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. | 0.973 |
CGA | POMC | ENSMODP00000056565 | ENSMODP00000019780 | Glycoprotein hormones alpha chain; Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH and follitropin/follicle stimulating hormone/FSH. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways. | Proopiomelanocortin. | 0.747 |
DHX34 | LHB | ENSMODP00000041692 | ENSMODP00000017212 | DExH-box helicase 34. | Lutropin subunit beta; Promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. | 0.559 |
F7C199_MONDO | LHB | ENSMODP00000025356 | ENSMODP00000017212 | NTF2 domain-containing protein. | Lutropin subunit beta; Promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. | 0.549 |
F7C199_MONDO | NUTF2 | ENSMODP00000025356 | ENSMODP00000006827 | NTF2 domain-containing protein. | NTF2 domain-containing protein. | 0.546 |
F7DCC2_MONDO | LHB | ENSMODP00000004236 | ENSMODP00000017212 | Uncharacterized protein. | Lutropin subunit beta; Promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. | 0.549 |
FOS | LHB | ENSMODP00000007329 | ENSMODP00000017212 | Fos proto-oncogene, AP-1 transcription factor subunit. | Lutropin subunit beta; Promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. | 0.665 |
FOS | POMC | ENSMODP00000007329 | ENSMODP00000019780 | Fos proto-oncogene, AP-1 transcription factor subunit. | Proopiomelanocortin. | 0.541 |
FSHR | CGA | ENSMODP00000001525 | ENSMODP00000056565 | Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. | Glycoprotein hormones alpha chain; Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH and follitropin/follicle stimulating hormone/FSH. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways. | 0.973 |
FSHR | LHB | ENSMODP00000001525 | ENSMODP00000017212 | Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. | Lutropin subunit beta; Promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. | 0.571 |
FSHR | POMC | ENSMODP00000001525 | ENSMODP00000019780 | Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. | Proopiomelanocortin. | 0.915 |
LHB | CGA | ENSMODP00000017212 | ENSMODP00000056565 | Lutropin subunit beta; Promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. | Glycoprotein hormones alpha chain; Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH and follitropin/follicle stimulating hormone/FSH. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways. | 0.995 |
LHB | DHX34 | ENSMODP00000017212 | ENSMODP00000041692 | Lutropin subunit beta; Promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. | DExH-box helicase 34. | 0.559 |
LHB | F7C199_MONDO | ENSMODP00000017212 | ENSMODP00000025356 | Lutropin subunit beta; Promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. | NTF2 domain-containing protein. | 0.549 |
LHB | F7DCC2_MONDO | ENSMODP00000017212 | ENSMODP00000004236 | Lutropin subunit beta; Promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. | Uncharacterized protein. | 0.549 |
LHB | FOS | ENSMODP00000017212 | ENSMODP00000007329 | Lutropin subunit beta; Promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. | Fos proto-oncogene, AP-1 transcription factor subunit. | 0.665 |
LHB | FSHR | ENSMODP00000017212 | ENSMODP00000001525 | Lutropin subunit beta; Promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. | Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. | 0.571 |
LHB | LHCGR | ENSMODP00000017212 | ENSMODP00000001486 | Lutropin subunit beta; Promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. | Lutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. | 0.966 |