STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC100011470Signal transducer and activator of transcription. (839 aa)    
Predicted Functional Partners:
JAK2
Tyrosine-protein kinase.
   
 0.971
JAK1
Protein kinase domain-containing protein.
   
 0.970
EGFR
Receptor protein-tyrosine kinase.
    
 0.969
STAT3
Signal transducer and activator of transcription.
   
0.967
TYK2
Tyrosine-protein kinase.
   
 0.966
IRF9
Interferon regulatory factor 9.
   
 0.965
STAT1
Signal transducer and activator of transcription.
   
0.955
ERBB4
Receptor protein-tyrosine kinase.
    
 0.950
FLT3
Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
   
 0.949
PTPN2
Tyrosine-protein phosphatase non-receptor type.
   
 0.948
Your Current Organism:
Monodelphis domestica
NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.