STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLEKHG6Pleckstrin homology and RhoGEF domain containing G6. (792 aa)    
Predicted Functional Partners:
TNF
Tumor necrosis factor; Belongs to the tumor necrosis factor family.
    
 0.773
TRADD
TNFRSF1A associated via death domain.
    
 0.761
RIPK1
Receptor interacting serine/threonine kinase 1.
   
 0.743
LTA
Lymphotoxin alpha; Belongs to the tumor necrosis factor family.
    
 0.731
CYLD
CYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family.
    
 0.710
RNF31
Uncharacterized protein.
    
 0.691
ARHGEF15
Rho guanine nucleotide exchange factor 15.
   
 0.685
RBCK1
RANBP2-type and C3HC4-type zinc finger containing 1.
    
 0.685
TNFAIP3
TNF alpha induced protein 3.
    
 0.683
SHARPIN
SHANK associated RH domain interactor.
    
 0.647
Your Current Organism:
Monodelphis domestica
NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.