node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CBFB | ETS1 | ENSMODP00000058251 | ENSMODP00000053252 | Core-binding factor subunit beta. | ETS proto-oncogene 1, transcription factor. | 0.639 |
CBFB | ETS2 | ENSMODP00000058251 | ENSMODP00000026243 | Core-binding factor subunit beta. | ETS proto-oncogene 2, transcription factor. | 0.466 |
CBFB | PAX2 | ENSMODP00000058251 | ENSMODP00000024149 | Core-binding factor subunit beta. | Paired box 2. | 0.481 |
CBFB | RUNX1 | ENSMODP00000058251 | ENSMODP00000026321 | Core-binding factor subunit beta. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.917 |
CBFB | RUNX2 | ENSMODP00000058251 | ENSMODP00000058316 | Core-binding factor subunit beta. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.917 |
CBFB | RUNX3 | ENSMODP00000058251 | ENSMODP00000045293 | Core-binding factor subunit beta. | Runt domain-containing protein. | 0.917 |
E2F1 | PAX2 | ENSMODP00000003492 | ENSMODP00000024149 | E2F transcription factor 1. | Paired box 2. | 0.465 |
ETS1 | CBFB | ENSMODP00000053252 | ENSMODP00000058251 | ETS proto-oncogene 1, transcription factor. | Core-binding factor subunit beta. | 0.639 |
ETS1 | ETS2 | ENSMODP00000053252 | ENSMODP00000026243 | ETS proto-oncogene 1, transcription factor. | ETS proto-oncogene 2, transcription factor. | 0.970 |
ETS1 | PAX2 | ENSMODP00000053252 | ENSMODP00000024149 | ETS proto-oncogene 1, transcription factor. | Paired box 2. | 0.797 |
ETS1 | RUNX1 | ENSMODP00000053252 | ENSMODP00000026321 | ETS proto-oncogene 1, transcription factor. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.788 |
ETS1 | RUNX2 | ENSMODP00000053252 | ENSMODP00000058316 | ETS proto-oncogene 1, transcription factor. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.756 |
ETS1 | RUNX3 | ENSMODP00000053252 | ENSMODP00000045293 | ETS proto-oncogene 1, transcription factor. | Runt domain-containing protein. | 0.756 |
ETS2 | CBFB | ENSMODP00000026243 | ENSMODP00000058251 | ETS proto-oncogene 2, transcription factor. | Core-binding factor subunit beta. | 0.466 |
ETS2 | ETS1 | ENSMODP00000026243 | ENSMODP00000053252 | ETS proto-oncogene 2, transcription factor. | ETS proto-oncogene 1, transcription factor. | 0.970 |
ETS2 | PAX2 | ENSMODP00000026243 | ENSMODP00000024149 | ETS proto-oncogene 2, transcription factor. | Paired box 2. | 0.601 |
ETS2 | RUNX1 | ENSMODP00000026243 | ENSMODP00000026321 | ETS proto-oncogene 2, transcription factor. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.648 |
ETS2 | RUNX2 | ENSMODP00000026243 | ENSMODP00000058316 | ETS proto-oncogene 2, transcription factor. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.648 |
ETS2 | RUNX3 | ENSMODP00000026243 | ENSMODP00000045293 | ETS proto-oncogene 2, transcription factor. | Runt domain-containing protein. | 0.720 |
ETV3 | PAX2 | ENSMODP00000020796 | ENSMODP00000024149 | ETS domain-containing protein. | Paired box 2. | 0.444 |