STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
THBDUncharacterized protein. (541 aa)    
Predicted Functional Partners:
F2
Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.
    
 0.998
PROC
Protein C, inactivator of coagulation factors Va and VIIIa.
    
 0.980
ENSMODP00000051378
MHC_I-like_Ag-recog domain-containing protein.
     
 0.828
PLAT
Plasminogen activator; Belongs to the peptidase S1 family.
   
 0.757
GAB1
GRB2 associated binding protein 1.
    
 0.704
F2R
Coagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family.
    
 0.675
TFPI
Tissue factor pathway inhibitor.
    
 
 0.671
F7
Coagulation factor VII.
    
 0.665
F3
Coagulation factor III, tissue factor.
      
 0.651
MAP3K2
Mitogen-activated protein kinase kinase kinase 2.
    
 0.649
Your Current Organism:
Monodelphis domestica
NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum
Server load: medium (70%) [HD]