DICER1 protein (Monodelphis domestica) - STRING interaction network

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Predicted Interactions

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Score

DICER1

Dicer 1, ribonuclease III; Belongs to the helicase family. Dicer subfamily. (1921 aa)

Predicted Functional Partners:

PRKRA

0.999

AGO2

0.992

DGCR8

0.950

AGO3

0.925

AGO4

0.925

AGO1

0.924

STAU1

0.921

STAU2

0.921

XPO5

0.907

MRPS9

0.874

Your Current Organism:

Monodelphis domestica

NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGO1	AGO2	ENSMODP00000049312	ENSMODP00000000899	Argonaute RISC component 1; Belongs to the argonaute family.	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	0.766
AGO1	DICER1	ENSMODP00000049312	ENSMODP00000059953	Argonaute RISC component 1; Belongs to the argonaute family.	Dicer 1, ribonuclease III; Belongs to the helicase family. Dicer subfamily.	0.924
AGO1	PRKRA	ENSMODP00000049312	ENSMODP00000012297	Argonaute RISC component 1; Belongs to the argonaute family.	Protein activator of interferon induced protein kinase EIF2AK2.	0.819
AGO1	STAU1	ENSMODP00000049312	ENSMODP00000020350	Argonaute RISC component 1; Belongs to the argonaute family.	Staufen double-stranded RNA binding protein 1.	0.697
AGO1	STAU2	ENSMODP00000049312	ENSMODP00000041997	Argonaute RISC component 1; Belongs to the argonaute family.	Staufen double-stranded RNA binding protein 2.	0.716
AGO1	XPO5	ENSMODP00000049312	ENSMODP00000023659	Argonaute RISC component 1; Belongs to the argonaute family.	Exportin 5.	0.666
AGO2	AGO1	ENSMODP00000000899	ENSMODP00000049312	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Argonaute RISC component 1; Belongs to the argonaute family.	0.766
AGO2	AGO3	ENSMODP00000000899	ENSMODP00000022277	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs.	0.843
AGO2	AGO4	ENSMODP00000000899	ENSMODP00000022278	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Argonaute RISC component 4; Belongs to the argonaute family.	0.842
AGO2	DGCR8	ENSMODP00000000899	ENSMODP00000012948	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	DGCR8 microprocessor complex subunit.	0.809
AGO2	DICER1	ENSMODP00000000899	ENSMODP00000059953	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Dicer 1, ribonuclease III; Belongs to the helicase family. Dicer subfamily.	0.992
AGO2	PRKRA	ENSMODP00000000899	ENSMODP00000012297	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Protein activator of interferon induced protein kinase EIF2AK2.	0.933
AGO2	STAU1	ENSMODP00000000899	ENSMODP00000020350	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Staufen double-stranded RNA binding protein 1.	0.651
AGO2	STAU2	ENSMODP00000000899	ENSMODP00000041997	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Staufen double-stranded RNA binding protein 2.	0.651
AGO2	XPO5	ENSMODP00000000899	ENSMODP00000023659	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Exportin 5.	0.845
AGO3	AGO2	ENSMODP00000022277	ENSMODP00000000899	Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs.	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	0.843
AGO3	DGCR8	ENSMODP00000022277	ENSMODP00000012948	Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs.	DGCR8 microprocessor complex subunit.	0.572
AGO3	DICER1	ENSMODP00000022277	ENSMODP00000059953	Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs.	Dicer 1, ribonuclease III; Belongs to the helicase family. Dicer subfamily.	0.925
AGO3	PRKRA	ENSMODP00000022277	ENSMODP00000012297	Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs.	Protein activator of interferon induced protein kinase EIF2AK2.	0.879
AGO3	STAU1	ENSMODP00000022277	ENSMODP00000020350	Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs.	Staufen double-stranded RNA binding protein 1.	0.651