node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AYL99_00039 | AYL99_00932 | A0A178ZWJ4 | A0A178ZYM1 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | GMP synthase. | 0.988 |
AYL99_00039 | AYL99_04256 | A0A178ZWJ4 | A0A178ZS93 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | S-methyl-5'-thioadenosine phosphorylase. | 0.846 |
AYL99_00039 | AYL99_05778 | A0A178ZWJ4 | A0A178ZN22 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 0.969 |
AYL99_00039 | AYL99_06858 | A0A178ZWJ4 | A0A178ZIF1 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | Adenine phosphoribosyltransferase. | 0.870 |
AYL99_00039 | AYL99_08175 | A0A178ZWJ4 | A0A178ZCD2 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | Uncharacterized protein. | 0.849 |
AYL99_00039 | AYL99_08819 | A0A178ZWJ4 | A0A178ZAB1 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.876 |
AYL99_00039 | AYL99_09192 | A0A178ZWJ4 | A0A178ZBC7 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | Uncharacterized protein. | 0.811 |
AYL99_00039 | AYL99_10802 | A0A178ZWJ4 | A0A178Z5W1 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | Bifunctional purine biosynthesis protein ADE17. | 0.887 |
AYL99_00932 | AYL99_00039 | A0A178ZYM1 | A0A178ZWJ4 | GMP synthase. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | 0.988 |
AYL99_00932 | AYL99_04256 | A0A178ZYM1 | A0A178ZS93 | GMP synthase. | S-methyl-5'-thioadenosine phosphorylase. | 0.769 |
AYL99_00932 | AYL99_05778 | A0A178ZYM1 | A0A178ZN22 | GMP synthase. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 0.701 |
AYL99_00932 | AYL99_06858 | A0A178ZYM1 | A0A178ZIF1 | GMP synthase. | Adenine phosphoribosyltransferase. | 0.981 |
AYL99_00932 | AYL99_08175 | A0A178ZYM1 | A0A178ZCD2 | GMP synthase. | Uncharacterized protein. | 0.722 |
AYL99_00932 | AYL99_08819 | A0A178ZYM1 | A0A178ZAB1 | GMP synthase. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.899 |
AYL99_00932 | AYL99_09192 | A0A178ZYM1 | A0A178ZBC7 | GMP synthase. | Uncharacterized protein. | 0.788 |
AYL99_00932 | AYL99_10802 | A0A178ZYM1 | A0A178Z5W1 | GMP synthase. | Bifunctional purine biosynthesis protein ADE17. | 0.732 |
AYL99_00932 | AYL99_11730 | A0A178ZYM1 | A0A178Z543 | GMP synthase. | IMPDH domain-containing protein. | 0.982 |
AYL99_04256 | AYL99_00039 | A0A178ZS93 | A0A178ZWJ4 | S-methyl-5'-thioadenosine phosphorylase. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | 0.846 |
AYL99_04256 | AYL99_00932 | A0A178ZS93 | A0A178ZYM1 | S-methyl-5'-thioadenosine phosphorylase. | GMP synthase. | 0.769 |
AYL99_04256 | AYL99_05778 | A0A178ZS93 | A0A178ZN22 | S-methyl-5'-thioadenosine phosphorylase. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 0.493 |