STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A1X2HCR1Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (247 aa)    
Predicted Functional Partners:
A0A1X2H6Z0
3-oxo-5-alpha-steroid 4-dehydrogenase-domain-containing protein.
   
 0.933
A0A1X2HAB2
Very-long-chain 3-oxoacyl-CoA reductase; Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3- ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids.
   
 0.889
A0A1X2HGY3
Uncharacterized protein.
   
 0.889
A0A1X2HGG1
Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.
     
 0.750
A0A1X2GZX0
Elongation of fatty acids protein.
    
 0.696
A0A1X2HM08
Elongation of fatty acids protein.
    
 0.696
A0A1X2HUF4
Elongation of fatty acids protein.
    
 0.696
A0A1X2HF79
Nuclear export factor CRM1.
    
 
 0.604
A0A1X2HN65
E3 ubiquitin ligase complex SCF subunit sconC; Belongs to the SKP1 family.
    
 
 0.603
A0A1X2H6D5
Delta-6 fatty acid desaturase.
     
 0.503
Your Current Organism:
Syncephalastrum racemosum
NCBI taxonomy Id: 13706
Other names: S. racemosum, fungal sp. RS07OS
Server load: low (30%) [HD]