STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IRF6Interferon regulatory factor 6. (460 aa)    
Predicted Functional Partners:
MYD88
MYD88 innate immune signal transduction adaptor.
   
 0.755
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.730
IFNAR1
Interferon alpha and beta receptor subunit 1.
   
  
 0.552
TLR4
Toll like receptor 4; Belongs to the Toll-like receptor family.
   
 
 0.524
TNIP1
TNFAIP3 interacting protein 1.
  
   
 0.523
SIRT1
Deacetylase sirtuin-type domain-containing protein.
    
 0.463
RIPK4
Receptor interacting serine/threonine kinase 4.
   
 0.456
STING1
Transmembrane protein 173.
   
 0.441
IL10
Interleukin 10.
   
 
 0.434
CREBBP
CREB binding protein.
    
 0.426
Your Current Organism:
Pelodiscus sinensis
NCBI taxonomy Id: 13735
Other names: Chinese soft-shelled turtle, Chinese softshell turtle, P. sinensis, Trionyx sinensis, ZMB 38
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.