STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCND1Cyclin D1; Belongs to the cyclin family. (292 aa)    
Predicted Functional Partners:
RB1
RB transcriptional corepressor 1.
    
 0.993
CDK6
Cyclin dependent kinase 6; Belongs to the protein kinase superfamily.
   
 0.993
CDK4
Cyclin dependent kinase 4.
   
 0.987
K7F1M4_PELSI
Uncharacterized protein.
   
 0.980
CDKN1C
Cyclin dependent kinase inhibitor 1C.
   
 0.980
CDKN1B
Cyclin dependent kinase inhibitor 1B.
   
 0.980
CDKN2A
Cyclin dependent kinase inhibitor 2A.
    
 0.976
RBL2
RB transcriptional corepressor like 2.
    
 0.971
CDKN2C
Cyclin dependent kinase inhibitor 2C.
    
 0.968
PCNA
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
    
 0.961
Your Current Organism:
Pelodiscus sinensis
NCBI taxonomy Id: 13735
Other names: Chinese soft-shelled turtle, Chinese softshell turtle, P. sinensis, Trionyx sinensis, ZMB 38
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