STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DSY0672Hypothetical protein; Similarity to COG1201 Lhr-like helicases(Evalue: 2E-70). (720 aa)    
Predicted Functional Partners:
DSY0671
Hypothetical protein.
     0.972
DSY0670
Hypothetical protein.
     0.951
DSY0673
Hypothetical protein; Similarity to COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster(Evalue: 3E-82).
 
    
0.487
DSY0863
Hypothetical protein; Similarity to COG0477 Permeases of the major facilitator superfamily(Evalue: 8E-21).
  
     0.461
DSY0674
Hypothetical protein; Similarity to COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster(Evalue: 1E-79).
 
    
0.446
DSY0942
Hypothetical protein; Similarity to COG0477 Permeases of the major facilitator superfamily(Evalue: 4E-31).
  
     0.431
radA
Hypothetical protein; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
   
  
 0.425
DSY0753
Hypothetical protein; Similarity to COG0266 Formamidopyrimidine-DNA glycosylase.
  
  
 0.422
mutM
Hypothetical protein; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
  
  
 0.422
DSY4101
Hypothetical protein; Similarity to COG0266 Formamidopyrimidine-DNA glycosylase(Evalue: 2E-34); Belongs to the FPG family.
  
  
 0.422
Your Current Organism:
Desulfitobacterium hafniense
NCBI taxonomy Id: 138119
Other names: D. hafniense Y51, Desulfitobacterium hafniense Y51, Desulfitobacterium hafniense str. Y51, Desulfitobacterium hafniense strain Y51, Desulfitobacterium sp. Y51
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.