STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
larCHypothetical protein; Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes. Belongs to the LarC family. (402 aa)    
Predicted Functional Partners:
DSY3982
Hypothetical protein; Similarity to COG1606 ATP-utilizing enzymes of the PP-loop superfamily(Evalue: 1E-65).
  
 0.986
DSY1760
Hypothetical protein; Similarity to COG1691 NCAIR mutase (PurE)-related proteins(Evalue: 1E-64).
  
 0.962
DSY3290
Hypothetical protein.
 
  
 0.748
DSY3250
Hypothetical protein.
 
  
 0.729
DSY3881
Hypothetical protein.
 
  
 0.696
pyrG
Hypothetical protein; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
      0.688
DSY1506
Hypothetical protein.
 
  
 0.557
DSY2210
Hypothetical protein; Similarity to COG0517 CBS domains(Evalue: 7E-45).
       0.544
cbiM
Cobalamin biosynthesis protein CbiM; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.
  
    0.527
DSY2944
Hypothetical protein; Similarity to COG2768 Uncharacterized Fe-S center protein(Evalue: 1E-110).
 
    0.467
Your Current Organism:
Desulfitobacterium hafniense
NCBI taxonomy Id: 138119
Other names: D. hafniense Y51, Desulfitobacterium hafniense Y51, Desulfitobacterium hafniense str. Y51, Desulfitobacterium hafniense strain Y51, Desulfitobacterium sp. Y51
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.