STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemLHypothetical protein; Similarity to COG0001 Glutamate-1-semialdehyde aminotransferase(Evalue: 1E-154). (430 aa)    
Predicted Functional Partners:
DSY2222
Hypothetical protein; Similarity to COG0113 Delta-aminolevulinic acid dehydratase(Evalue: 1E-118); Belongs to the ALAD family.
 
 
 0.998
hemA
Hypothetical protein; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
 0.997
hemC
Hypothetical protein; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
 0.988
DSY2224
Hypothetical protein; Similarity to COG0007 Uroporphyrinogen-III methylase(Evalue: 8E-75).
 
  
 0.976
cysG
Putative precorrin-2 oxidase; Similarity to COG1648 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain)(Evalue: 7E-34).
   
 0.976
DSY2822
Hypothetical protein; Similarity to COG1020 Non-ribosomal peptide synthetase modules and related proteins(Evalue: 1E-179); Belongs to the ATP-dependent AMP-binding enzyme family.
  
 
 0.951
dltA
Hypothetical protein; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to the ATP-dependent AMP-bindin [...]
  
 
 0.943
DSY2661
Hypothetical protein; Similarity to COG0331 (acyl-carrier-protein) S-malonyltransferase(Evalue: 2E-74).
    
 0.887
DSY2220
Hypothetical protein; Similarity to COG1522 Transcriptional regulators(Evalue: 3E-42).
     
 0.844
DSY2221
Hypothetical protein; Similarity to COG0535 Predicted Fe-S oxidoreductases(Evalue: 1E-57).
 
  
 0.830
Your Current Organism:
Desulfitobacterium hafniense
NCBI taxonomy Id: 138119
Other names: D. hafniense Y51, Desulfitobacterium hafniense Y51, Desulfitobacterium hafniense str. Y51, Desulfitobacterium hafniense strain Y51, Desulfitobacterium sp. Y51
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