STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemAHypothetical protein; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (443 aa)    
Predicted Functional Partners:
hemC
Hypothetical protein; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
 0.999
hemL
Hypothetical protein; Similarity to COG0001 Glutamate-1-semialdehyde aminotransferase(Evalue: 1E-154).
 
 0.997
DSY2224
Hypothetical protein; Similarity to COG0007 Uroporphyrinogen-III methylase(Evalue: 8E-75).
 
  
 0.985
DSY2222
Hypothetical protein; Similarity to COG0113 Delta-aminolevulinic acid dehydratase(Evalue: 1E-118); Belongs to the ALAD family.
 
  
 0.965
cysG
Putative precorrin-2 oxidase; Similarity to COG1648 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain)(Evalue: 7E-34).
 
   
 0.923
ccsA
Similarity to COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component(Evalue: 5E-53).
 
  
 0.795
DSY2223
Hypothetical protein; Similarity to COG0535 Predicted Fe-S oxidoreductases(Evalue: 1E-94).
 
   
 0.789
DSY2220
Hypothetical protein; Similarity to COG1522 Transcriptional regulators(Evalue: 3E-42).
 
   
 0.749
DSY2221
Hypothetical protein; Similarity to COG0535 Predicted Fe-S oxidoreductases(Evalue: 1E-57).
 
   
 0.703
resB
Similarity to COG1333 ResB protein required for cytochrome c biosynthesis(Evalue: 1E-29).
 
   
 0.616
Your Current Organism:
Desulfitobacterium hafniense
NCBI taxonomy Id: 138119
Other names: D. hafniense Y51, Desulfitobacterium hafniense Y51, Desulfitobacterium hafniense str. Y51, Desulfitobacterium hafniense strain Y51, Desulfitobacterium sp. Y51
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