STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DSY3883Hypothetical protein; Similarity to COG0119 Isopropylmalate/homocitrate/citramalate synthases(Evalue: 5E-90); Belongs to the alpha-IPM synthase/homocitrate synthase family. (387 aa)    
Predicted Functional Partners:
porA
Similarity to COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit(Evalue: 1E-165).
  
 
 0.955
porA-2
Similarity to COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit(Evalue: 1E-156).
  
 
 0.953
DSY2366
Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
  
 
 0.944
acsA
Hypothetical protein; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 
 0.918
DSY0406
Hypothetical protein; Similarity to COG1012 NAD-dependent aldehyde dehydrogenases(Evalue: 1E-102).
  
 0.915
DSY0970
Hypothetical protein; Similarity to COG0119 Isopropylmalate/homocitrate/citramalate synthases(Evalue: 1E-70); Belongs to the alpha-IPM synthase/homocitrate synthase family.
  
  
 
0.915
leuB
Hypothetical protein; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
 
 0.915
DSY4993
Hypothetical protein; Similarity to COG1012 NAD-dependent aldehyde dehydrogenases(Evalue: 1E-111).
  
 0.915
DSY4262
Hypothetical protein; Similarity to COG0119 Isopropylmalate/homocitrate/citramalate synthases(Evalue: 1E-64); Belongs to the alpha-IPM synthase/homocitrate synthase family.
  
  
 
0.910
accA
Hypothetical protein; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
    
  0.901
Your Current Organism:
Desulfitobacterium hafniense
NCBI taxonomy Id: 138119
Other names: D. hafniense Y51, Desulfitobacterium hafniense Y51, Desulfitobacterium hafniense str. Y51, Desulfitobacterium hafniense strain Y51, Desulfitobacterium sp. Y51
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.