STRINGSTRING
purM protein (Desulfitobacterium hafniense) - STRING interaction network
"purM" - Phosphoribosylformylglycinamidine cyclo-ligase in Desulfitobacterium hafniense
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
purMPhosphoribosylformylglycinamidine cyclo-ligase; Similarity to COG0150 Phosphoribosylaminoimidazol (AIR) synthetase(Evalue- 1E-114) (339 aa)    
Predicted Functional Partners:
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine (472 aa)
 
  0.999
DSY3934
Uncharacterized protein; Similarity to COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain(Evalue- 0) (1290 aa)
 
  0.999
purN
Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate (217 aa)
   
  0.999
purD
Similarity to COG0151 Phosphoribosylamine-glycine ligase(Evalue- 1E-113); Belongs to the GARS family (419 aa)
 
  0.999
purH
Bifunctional purine biosynthesis protein PurH; Similarity to COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful)(Evalue- 1E-155) (518 aa)
 
 
  0.996
purE
N5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (164 aa)
 
   
  0.980
purC
Similarity to COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase(Evalue- 5E-75); Belongs to the SAICAR synthetase family (238 aa)
 
   
  0.959
guaA
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP (510 aa)
 
   
  0.865
DSY4957
Uncharacterized protein; Similarity to COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ) (396 aa)
   
   
  0.864
thiC
Phosphomethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction; Belongs to the ThiC family (435 aa)
   
 
  0.810
Your Current Organism:
Desulfitobacterium hafniense
NCBI taxonomy Id: 138119
Other names: D. hafniense Y51, Desulfitobacterium hafniense, Desulfitobacterium hafniense Y51, Desulfitobacterium hafniense str. Y51, Desulfitobacterium hafniense strain Y51, Desulfitobacterium sp. Y51
Server load: low (7%) [HD]