STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
topBHypothetical protein; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA sup [...] (729 aa)    
Predicted Functional Partners:
DSY0682
Hypothetical protein; Similarity to COG0514 Superfamily II DNA helicase(Evalue: 5E-52).
  
 0.962
DSY0718
Hypothetical protein; Similarity to COG0514 Superfamily II DNA helicase(Evalue: 6E-56).
  
 0.962
DSY1775
Hypothetical protein; Similarity to COG0514 Superfamily II DNA helicase(Evalue: 1E-172).
 
 0.944
porA
Similarity to COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit(Evalue: 1E-165).
  
   0.925
porA-2
Similarity to COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit(Evalue: 1E-156).
  
   0.907
DSY2197
Hypothetical protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
  
 
 0.901
leuS
Hypothetical protein; Similarity to COG0495 Leucyl-tRNA synthetase(Evalue: 0); Belongs to the class-I aminoacyl-tRNA synthetase family.
   
 
 0.901
DSY5035
Hypothetical protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
  
 
 0.901
DSY0713
Hypothetical protein; Similarity to COG0514 Superfamily II DNA helicase(Evalue: 1E-53).
 
 0.893
DSY4385
Hypothetical protein; Similarity to COG0069 Glutamate synthase domain 2(Evalue: 0).
  
  
 0.863
Your Current Organism:
Desulfitobacterium hafniense
NCBI taxonomy Id: 138119
Other names: D. hafniense Y51, Desulfitobacterium hafniense Y51, Desulfitobacterium hafniense str. Y51, Desulfitobacterium hafniense strain Y51, Desulfitobacterium sp. Y51
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