STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKJ08_0208Cytochrome c-type biogenesis protein CcmE, heme chaperone; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. (154 aa)    
Predicted Functional Partners:
AKJ08_0210
Cytochrome c-type biogenesis protein CcmC, putative heme lyase for CcmE.
 
 
 0.996
AKJ08_0207
Cytochrome c heme lyase subunit CcmF.
 
 
 0.981
AKJ08_0205
Cytochrome c heme lyase subunit CcmL; Possible subunit of a heme lyase.
 
  
 0.972
AKJ08_0211
ABC transporter involved in cytochrome c biogenesis, CcmB subunit; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family.
 
 
 0.967
AKJ08_0206
Cytochrome c-type biogenesis protein CcmG/DsbE, thiol:disulfide oxidoreductase.
 
  
 0.958
AKJ08_0204
Cytochrome c heme lyase subunit CcmH.
 
  
 0.888
AKJ08_0203
Hypothetical protein.
       0.529
AKJ08_0212
ABC transporter involved in cytochrome c biogenesis, ATPase component CcmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.
       0.514
AKJ08_3194
Cytochrome c oxidase polypeptide II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
     
 0.432
AKJ08_1625
Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
      
 0.429
Your Current Organism:
Vulgatibacter incomptus
NCBI taxonomy Id: 1391653
Other names: Cystobacteraceae bacterium B00001, DSM 27710, NBRC 109945, V. incomptus, Vulgatibacter incomptus Yamamoto et al. 2014, strain B00001
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