node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KCZ70637.1 | KCZ72384.1 | ANME2D_02658 | ANME2D_00811 | Sucrose-phosphate phosphatase-like hydrolase, Archaeal; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: phosphoglycolate phosphatase, TA0175-type; sucrose-phosphate phosphatase subfamily. | 2, 5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 1'-reductase; PFAM: RibD C-terminal domain; TIGRFAM: riboflavin-specific deaminase C-terminal domain; 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 1'-reductase, archaeal. | 0.785 |
KCZ70637.1 | KCZ72610.1 | ANME2D_02658 | ANME2D_01040 | Sucrose-phosphate phosphatase-like hydrolase, Archaeal; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: phosphoglycolate phosphatase, TA0175-type; sucrose-phosphate phosphatase subfamily. | PFAM: Haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED. | 0.863 |
KCZ70637.1 | ribB | ANME2D_02658 | ANME2D_02209 | Sucrose-phosphate phosphatase-like hydrolase, Archaeal; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: phosphoglycolate phosphatase, TA0175-type; sucrose-phosphate phosphatase subfamily. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | 0.435 |
KCZ70637.1 | ribH | ANME2D_02658 | ANME2D_01173 | Sucrose-phosphate phosphatase-like hydrolase, Archaeal; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: phosphoglycolate phosphatase, TA0175-type; sucrose-phosphate phosphatase subfamily. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.787 |
KCZ72384.1 | KCZ70637.1 | ANME2D_00811 | ANME2D_02658 | 2, 5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 1'-reductase; PFAM: RibD C-terminal domain; TIGRFAM: riboflavin-specific deaminase C-terminal domain; 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 1'-reductase, archaeal. | Sucrose-phosphate phosphatase-like hydrolase, Archaeal; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: phosphoglycolate phosphatase, TA0175-type; sucrose-phosphate phosphatase subfamily. | 0.785 |
KCZ72384.1 | KCZ72610.1 | ANME2D_00811 | ANME2D_01040 | 2, 5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 1'-reductase; PFAM: RibD C-terminal domain; TIGRFAM: riboflavin-specific deaminase C-terminal domain; 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 1'-reductase, archaeal. | PFAM: Haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED. | 0.711 |
KCZ72384.1 | ribB | ANME2D_00811 | ANME2D_02209 | 2, 5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 1'-reductase; PFAM: RibD C-terminal domain; TIGRFAM: riboflavin-specific deaminase C-terminal domain; 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 1'-reductase, archaeal. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | 0.985 |
KCZ72384.1 | ribH | ANME2D_00811 | ANME2D_01173 | 2, 5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 1'-reductase; PFAM: RibD C-terminal domain; TIGRFAM: riboflavin-specific deaminase C-terminal domain; 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 1'-reductase, archaeal. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.982 |
KCZ72503.1 | ribH | ANME2D_00930 | ANME2D_01173 | K+ transport system, NAD-binding component; PFAM: TrkA-N domain; TrkA-C domain. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.922 |
KCZ72610.1 | KCZ70637.1 | ANME2D_01040 | ANME2D_02658 | PFAM: Haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED. | Sucrose-phosphate phosphatase-like hydrolase, Archaeal; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: phosphoglycolate phosphatase, TA0175-type; sucrose-phosphate phosphatase subfamily. | 0.863 |
KCZ72610.1 | KCZ72384.1 | ANME2D_01040 | ANME2D_00811 | PFAM: Haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED. | 2, 5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 1'-reductase; PFAM: RibD C-terminal domain; TIGRFAM: riboflavin-specific deaminase C-terminal domain; 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 1'-reductase, archaeal. | 0.711 |
KCZ72610.1 | nadC | ANME2D_01040 | ANME2D_01034 | PFAM: Haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED. | Nicotinate-nucleotide pyrophosphorylase (carboxylating); Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. | 0.705 |
KCZ72610.1 | ribH | ANME2D_01040 | ANME2D_01173 | PFAM: Haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.739 |
nadC | KCZ72610.1 | ANME2D_01034 | ANME2D_01040 | Nicotinate-nucleotide pyrophosphorylase (carboxylating); Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. | PFAM: Haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED. | 0.705 |
nadC | pyrB | ANME2D_01034 | ANME2D_00390 | Nicotinate-nucleotide pyrophosphorylase (carboxylating); Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. | PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; TIGRFAM: aspartate carbamoyltransferase. | 0.827 |
nadC | ribH | ANME2D_01034 | ANME2D_01173 | Nicotinate-nucleotide pyrophosphorylase (carboxylating); Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.666 |
pyrB | nadC | ANME2D_00390 | ANME2D_01034 | PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; TIGRFAM: aspartate carbamoyltransferase. | Nicotinate-nucleotide pyrophosphorylase (carboxylating); Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. | 0.827 |
pyrB | ribB | ANME2D_00390 | ANME2D_02209 | PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; TIGRFAM: aspartate carbamoyltransferase. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | 0.425 |
pyrB | ribH | ANME2D_00390 | ANME2D_01173 | PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; TIGRFAM: aspartate carbamoyltransferase. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.871 |
ribB | KCZ70637.1 | ANME2D_02209 | ANME2D_02658 | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | Sucrose-phosphate phosphatase-like hydrolase, Archaeal; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: phosphoglycolate phosphatase, TA0175-type; sucrose-phosphate phosphatase subfamily. | 0.435 |