Known metabolic pathways, protein complexes, signal transduction pathways, etc ... from curated databases.
Genes that are sometimes fused into single open reading frames.
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
from curated databases
Putative transcriptional regulator YwtF; lytR_cpsA_psr- cell envelope-related function transcriptional attenuator common domain protein (345 aa)
Predicted Functional Partners:
Uncharacterized protein (332 aa)
sigma70-ECF- RNA polymerase sigma factor, sigma-70 family protein (177 aa)
annotation not available (117 aa)
C4-dicarboxylate transport protein; Sodium-dicarboxylate symporter family protein; Belongs to the dicarboxylate/amino acid-cation symporter (DAACS) (TC 2.A.23) family (420 aa)
Cell division protein SepF; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (156 aa)