STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aflCNorsolorinic acid synthase; Norsolorinic acid synthase; part of the gene cluster that mediates the biosynthesis of aflatoxins, a group of polyketide-derived furanocoumarins, and part of the most toxic and carcinogenic compounds among the known mycotoxins. The four major aflatoxins produced by A.parasiticus are aflatoxin B1 (AFB1), aflatoxin B2 (AFB2), aflatoxin G1 (AFG1) and aflatoxin G2 (AFG2). The first step of the pathway is the conversion of acetate to norsolorinic acid (NOR) and requires the fatty acid synthase subunits aflA and aflB, as well as the PKS aflC. AflC combines a hexan [...] (2109 aa)    
Predicted Functional Partners:
P875_00042289
Acetyl-CoA carboxylase central region.
   
 
 0.909
aflM
Versicolorin reductase 1; Versicolorin reductase; part of the gene cluster that mediates the biosynthesis of aflatoxins, a group of polyketide-derived furanocoumarins, and part of the most toxic and carcinogenic compounds among the known mycotoxins. The four major aflatoxins produced by A.parasiticus are aflatoxin B1 (AFB1), aflatoxin B2 (AFB2), aflatoxin G1 (AFG1) and aflatoxin G2 (AFG2). The first step of the pathway is the conversion of acetate to norsolorinic acid (NOR) and requires the fatty acid synthase subunits aflA and aflB, as well as the PKS aflC. AflC combines a hexanoyl st [...]
   
 0.673
P875_00042266
Sfp.
   
 0.670
P875_00021866
Medium chain dehydrogenases/reductase MDR/zinc-dependent alcohol dehydrogenase-like family protein.
    
 0.659
P875_00042951
The adenylation A domain of siderophore-synthesizing nonribosomal peptide synthetases NRPS.
  
 0.645
P875_00064808
AMP-binding enzyme.
 
 0.644
P875_00064745
AMP-binding enzyme.
  
  0.639
P875_00128055
AMP-binding enzyme.
  
  0.627
P875_00064850
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
    
 0.620
P875_00086334
KR domain protein.
 
     0.608
Your Current Organism:
Aspergillus parasiticus
NCBI taxonomy Id: 1403190
Other names: A. parasiticus SU-1, Aspergillus parasiticus SU-1
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