STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rpeRpa-associated phosphoesterase. (245 aa)    
Predicted Functional Partners:
rpap1
Rpa-associated protein.
 
   
 0.996
rpa1
Replication protein A.
 
     0.987
rpap3
Rpa-associated protein.
  
   
 0.857
lhr1
ATP-dependent DNA helicase.
 
    0.833
orc1
Orc1-type DNA replication protein; Involved in regulation of DNA replication.
  
     0.652
endA
tRNA-splicing endonuclease; Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5' and 3' splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp.
  
     0.639
trpA
Tryptophan synthase alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
      
 0.628
arfC
2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase.
       0.597
spt4
Transcription elongation factor Spt4; Stimulates transcription elongation; Belongs to the archaeal Spt4 family.
  
     0.584
atpF
A-type ATP synthase subunit F; Produces ATP from ADP in the presence of a proton gradient across the membrane.
  
     0.581
Your Current Organism:
Halobacterium hubeiense
NCBI taxonomy Id: 1407499
Other names: H. hubeiense, HAMBI 3616, Halobacterium sp. JI20-1, strain JI20-1
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.