STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KXG43009.1Peptidase M24; Derived by automated computational analysis using gene prediction method: Protein Homology. (396 aa)    
Predicted Functional Partners:
guaB
IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
   0.797
KXG44981.1
Helix-turn-helix transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.524
KXG43007.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.510
KXG43008.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.510
metG
methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family.
   
 
 0.497
gcvT
Glycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine.
  
 0.489
KXG43334.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.459
KXG44079.1
tRNA CCA-pyrophosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.433
ileS
isoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
 
 
 
 0.429
KXG44995.1
CMP deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.424
Your Current Organism:
Tepidibacillus decaturensis
NCBI taxonomy Id: 1413211
Other names: ATCC BAA-2644, DSM 103037, T. decaturensis, Tepidibacillus decaturensis Dong et al. 2016, Tepidibacillus sp. Z9, Tepidibacillus sp. Z9_1, Tepidibacillus sp. Z9_2, strain Z9
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.