STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRL87603.15-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (183 aa)    
Predicted Functional Partners:
folD
Methylenetetrahydrofolate dehydrogenase (nadp+) methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
    
 0.951
purN
Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
   
 0.947
KRL86851.1
Membrane-associated serine protease.
  
    0.831
KRL87602.1
Hypothetical protein.
       0.795
fhs
Fhs protein; Belongs to the formate--tetrahydrofolate ligase family.
   
 0.674
KRL87604.1
Auxin efflux carrier (AEC) family permease.
       0.620
purH
Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase IMP cyclohydrolase.
    
 0.601
fmt
Methionyl-trna formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.
   
 
 0.594
glyQ
glycyl-tRNA synthetase subunit alpha.
   
    0.553
pheT
phenylalanyl-tRNA synthetase subunit beta; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
  
  
 0.547
Your Current Organism:
Lactobacillus pantheris
NCBI taxonomy Id: 1423783
Other names: L. pantheris DSM 15945 = JCM 12539 = NBRC 106106, Lactobacillus pantheris DSM 15945, Lactobacillus pantheris DSM 15945 = JCM 12539 = NBRC 106106, Lactobacillus pantheris JCM 12539, Lactobacillus pantheris NBRC 106106
Server load: low (28%) [HD]