node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EEJ40211.1 | EEJ40212.1 | HMPREF0549_1346 | HMPREF0549_1347 | Hypothetical protein. | Drug resistance MFS transporter, drug:H+ antiporter-2 family; COG: COG0477; Belongs to the major facilitator superfamily. | 0.858 |
EEJ40211.1 | EEJ40213.1 | HMPREF0549_1346 | HMPREF0549_1348 | Hypothetical protein. | Transcriptional regulator, MerR family. | 0.926 |
EEJ40212.1 | EEJ40211.1 | HMPREF0549_1347 | HMPREF0549_1346 | Drug resistance MFS transporter, drug:H+ antiporter-2 family; COG: COG0477; Belongs to the major facilitator superfamily. | Hypothetical protein. | 0.858 |
EEJ40212.1 | EEJ40213.1 | HMPREF0549_1347 | HMPREF0549_1348 | Drug resistance MFS transporter, drug:H+ antiporter-2 family; COG: COG0477; Belongs to the major facilitator superfamily. | Transcriptional regulator, MerR family. | 0.662 |
EEJ40213.1 | EEJ40211.1 | HMPREF0549_1348 | HMPREF0549_1346 | Transcriptional regulator, MerR family. | Hypothetical protein. | 0.926 |
EEJ40213.1 | EEJ40212.1 | HMPREF0549_1348 | HMPREF0549_1347 | Transcriptional regulator, MerR family. | Drug resistance MFS transporter, drug:H+ antiporter-2 family; COG: COG0477; Belongs to the major facilitator superfamily. | 0.662 |
EEJ40213.1 | accD | HMPREF0549_1348 | HMPREF0549_1055 | Transcriptional regulator, MerR family. | acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. | 0.646 |
EEJ40213.1 | dnaJ | HMPREF0549_1348 | HMPREF0549_0296 | Transcriptional regulator, MerR family. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.852 |
EEJ40213.1 | glnA | HMPREF0549_1348 | HMPREF0549_1689 | Transcriptional regulator, MerR family. | Glutamine synthetase, type I; COG: COG0174. | 0.746 |
EEJ40213.1 | rpoA | HMPREF0549_1348 | HMPREF0549_1410 | Transcriptional regulator, MerR family. | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.748 |
EEJ40213.1 | rpoB | HMPREF0549_1348 | HMPREF0549_1373 | Transcriptional regulator, MerR family. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.785 |
EEJ40213.1 | rpoC | HMPREF0549_1348 | HMPREF0549_1374 | Transcriptional regulator, MerR family. | DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.743 |
EEJ40213.1 | rpoD | HMPREF0549_1348 | HMPREF0549_0350 | Transcriptional regulator, MerR family. | RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.781 |
EEJ40213.1 | rpoZ | HMPREF0549_1348 | HMPREF0549_1715 | Transcriptional regulator, MerR family. | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.744 |
accD | EEJ40213.1 | HMPREF0549_1055 | HMPREF0549_1348 | acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. | Transcriptional regulator, MerR family. | 0.646 |
accD | rpoB | HMPREF0549_1055 | HMPREF0549_1373 | acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.460 |
accD | rpoC | HMPREF0549_1055 | HMPREF0549_1374 | acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. | DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.405 |
dnaJ | EEJ40213.1 | HMPREF0549_0296 | HMPREF0549_1348 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Transcriptional regulator, MerR family. | 0.852 |
dnaJ | rpoB | HMPREF0549_0296 | HMPREF0549_1373 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.461 |
dnaJ | rpoD | HMPREF0549_0296 | HMPREF0549_0350 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.737 |