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mutL protein (Zobellia uliginosa) - STRING interaction network
"mutL" - DNA mismatch repair protein MutL in Zobellia uliginosa
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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mutLDNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a "molecular matchmaker", a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (616 aa)    
Predicted Functional Partners:
mutS
DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity (860 aa)
  0.952
JQMD01000002_gene1501
annotation not available (288 aa)
              0.889
JQMD01000002_gene1500
annotation not available (247 aa)
              0.889
JQMD01000002_gene1498
annotation not available (99 aa)
              0.889
JQMD01000002_gene3686
annotation not available (590 aa)
 
  0.851
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5’-3’ exonuclease activity (946 aa)
   
  0.839
JQMD01000002_gene2459
annotation not available (471 aa)
       
  0.815
JQMD01000002_gene1008
Endonuclease MutS2; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity (723 aa)
   
   
  0.803
JQMD01000002_gene1330
Beta sliding clamp; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3’-5’ exonuclease proofreading activity. The beta chain is required for initiation of replication as [...] (372 aa)
   
  0.774
uvrB
UvrABC system protein B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and [...] (662 aa)
       
  0.750
Your Current Organism:
Zobellia uliginosa
NCBI taxonomy Id: 143224
Other names: ACAM 538, ATCC 14397, Agarbacterium uliginosum, CCUG 33448, CECT 4277, CIP 104808, Cellulophaga uliginosa, Cytophaga uliginosa, DSM 2061, Flavibacterium uliginosum, Flavobacterium uliginosum, IFO 14962, JCM 21152, LMG 3809, NBRC 14962, Z. uliginosa, Zobellia uliginosa, strain ZoBell 553
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