STRINGSTRING
lon protein (Zobellia uliginosa) - STRING interaction network
"lon" - Lon protease in Zobellia uliginosa
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lonLon protease; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (822 aa)    
Predicted Functional Partners:
clpX
ATP-dependent Clp protease ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (411 aa)
 
 
  0.895
JQMD01000002_gene1959
annotation not available (230 aa)
              0.873
JQMD01000002_gene1961
annotation not available (69 aa)
              0.774
ftsH
ATP-dependent zinc metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family (667 aa)
 
 
  0.728
JQMD01000002_gene2057
Chaperone protein HtpG; Molecular chaperone. Has ATPase activity (630 aa)
     
   
  0.721
dnaK
Chaperone protein DnaK; Acts as a chaperone (635 aa)
 
 
  0.676
JQMD01000002_gene4144
annotation not available (181 aa)
   
 
  0.651
groL
60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (543 aa)
   
 
  0.612
JQMD01000002_gene1962
annotation not available (171 aa)
              0.610
JQMD01000002_gene1964
annotation not available (363 aa)
              0.607
Your Current Organism:
Zobellia uliginosa
NCBI taxonomy Id: 143224
Other names: ACAM 538, ATCC 14397, Agarbacterium uliginosum, CCUG 33448, CECT 4277, CIP 104808, Cellulophaga uliginosa, Cytophaga uliginosa, DSM 2061, Flavibacterium uliginosum, Flavobacterium uliginosum, IFO 14962, JCM 21152, LMG 3809, NBRC 14962, Z. uliginosa, Zobellia uliginosa, strain ZoBell 553
Server load: low (7%) [HD]