node1 | node2 | node1 annotation | node2 annotation | score |
A0A2T2N4T2 | A0A2T2NIQ1 | HAD-like protein. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | 0.808 |
A0A2T2N4T2 | A0A2T2NL48 | HAD-like protein. | HAD-superfamily hydrolase. | 0.402 |
A0A2T2N4T2 | A0A2T2NN06 | HAD-like protein. | Phosphatidyl synthase-like protein. | 0.402 |
A0A2T2N4T2 | A0A2T2NNE8 | HAD-like protein. | Alpha/beta-hydrolase. | 0.855 |
A0A2T2N4T2 | A0A2T2NY69 | HAD-like protein. | HAD-superfamily hydrolase. | 0.402 |
A0A2T2N4T2 | A0A2T2NZY2 | HAD-like protein. | Uncharacterized protein; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.402 |
A0A2T2N4T2 | A0A2T2P0M6 | HAD-like protein. | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.740 |
A0A2T2N4T2 | A0A2T2PBW0 | HAD-like protein. | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | 0.740 |
A0A2T2N4T2 | A0A2T2PC24 | HAD-like protein. | Nicotinamide-nucleotide adenylyltransferase; Belongs to the eukaryotic NMN adenylyltransferase family. | 0.786 |
A0A2T2NAL9 | A0A2T2NNE8 | Nitroreductase. | Alpha/beta-hydrolase. | 0.838 |
A0A2T2NIQ1 | A0A2T2N4T2 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | HAD-like protein. | 0.808 |
A0A2T2NIQ1 | A0A2T2NL48 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | HAD-superfamily hydrolase. | 0.731 |
A0A2T2NIQ1 | A0A2T2NN06 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | Phosphatidyl synthase-like protein. | 0.731 |
A0A2T2NIQ1 | A0A2T2NNE8 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | Alpha/beta-hydrolase. | 0.864 |
A0A2T2NIQ1 | A0A2T2NY69 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | HAD-superfamily hydrolase. | 0.731 |
A0A2T2NIQ1 | A0A2T2NZY2 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | Uncharacterized protein; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.731 |
A0A2T2NIQ1 | A0A2T2P0M6 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.856 |
A0A2T2NIQ1 | A0A2T2PBW0 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | 0.831 |
A0A2T2NIQ1 | A0A2T2PC24 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | Nicotinamide-nucleotide adenylyltransferase; Belongs to the eukaryotic NMN adenylyltransferase family. | 0.511 |
A0A2T2NL48 | A0A2T2N4T2 | HAD-superfamily hydrolase. | HAD-like protein. | 0.402 |