STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KCV80741.1COG3103 SH3 domain protein. (180 aa)    
Predicted Functional Partners:
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
    
  0.815
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
  0.809
KCV81862.1
Sporulation related protein; COG3087 Cell division protein.
  
  
  0.654
KCV83211.1
Hypothetical protein; COG1196 Chromosome segregation ATPases.
  
     0.573
parC
DNA topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
       0.534
KCV82460.1
COG0794 Predicted sugar phosphate isomerase involved in capsule formation; Belongs to the SIS family. GutQ/KpsF subfamily.
    
  0.528
KCV80742.1
Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
    0.526
KCV83303.1
COG0438 Glycosyltransferase.
  
     0.511
KCV81631.1
Hypothetical protein.
  
     0.501
KCV83312.1
COG3206 Uncharacterized protein involved in exopolysaccharide biosynthesis.
 
     0.493
Your Current Organism:
Actibacterium atlanticum
NCBI taxonomy Id: 1461693
Other names: A. atlanticum, Actibacterium atlanticum Li et al. 2015, Actibacterium sp. 22II-S11-z10, LMG 27158, LMG:27158, MCCC 1A09298, strain 22II-S11-z10
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