node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABM70010.1 | hemL | A9601_07241 | A9601_05391 | COG1836 Predicted membrane protein [Function unknown]. | COG1 Glutamate-1-semialdehyde aminotransferase [Coenzyme metabolism]; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily. | 0.655 |
ABM70747.1 | fabD | A9601_14641 | A9601_01541 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | COG331 (acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]. | 0.517 |
ABM70747.1 | guaA | A9601_14641 | A9601_00361 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Glutamine amidotransferase class-I:GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.613 |
ABM70747.1 | hemA | A9601_14641 | A9601_08301 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.427 |
ABM70747.1 | hemB | A9601_14641 | A9601_02351 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | COG113 Delta-aminolevulinic acid dehydratase [Coenzyme metabolism]; Belongs to the ALAD family. | 0.540 |
ABM70747.1 | hemC | A9601_14641 | A9601_05521 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. | 0.441 |
ABM70747.1 | hemD | A9601_14641 | A9601_01311 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Putative uroporphyrinogen III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.509 |
ABM70747.1 | hemL | A9601_14641 | A9601_05391 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | COG1 Glutamate-1-semialdehyde aminotransferase [Coenzyme metabolism]; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily. | 0.527 |
fabD | ABM70747.1 | A9601_01541 | A9601_14641 | COG331 (acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.517 |
fabD | guaA | A9601_01541 | A9601_00361 | COG331 (acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]. | Glutamine amidotransferase class-I:GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.438 |
fabD | hemL | A9601_01541 | A9601_05391 | COG331 (acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]. | COG1 Glutamate-1-semialdehyde aminotransferase [Coenzyme metabolism]; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily. | 0.521 |
guaA | ABM70747.1 | A9601_00361 | A9601_14641 | Glutamine amidotransferase class-I:GMP synthase; Catalyzes the synthesis of GMP from XMP. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.613 |
guaA | fabD | A9601_00361 | A9601_01541 | Glutamine amidotransferase class-I:GMP synthase; Catalyzes the synthesis of GMP from XMP. | COG331 (acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]. | 0.438 |
guaA | hemB | A9601_00361 | A9601_02351 | Glutamine amidotransferase class-I:GMP synthase; Catalyzes the synthesis of GMP from XMP. | COG113 Delta-aminolevulinic acid dehydratase [Coenzyme metabolism]; Belongs to the ALAD family. | 0.407 |
guaA | hemE | A9601_00361 | A9601_06391 | Glutamine amidotransferase class-I:GMP synthase; Catalyzes the synthesis of GMP from XMP. | Uroporphyrinogen decarboxylase (URO-D); Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.465 |
guaA | hemL | A9601_00361 | A9601_05391 | Glutamine amidotransferase class-I:GMP synthase; Catalyzes the synthesis of GMP from XMP. | COG1 Glutamate-1-semialdehyde aminotransferase [Coenzyme metabolism]; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily. | 0.536 |
hemA | ABM70747.1 | A9601_08301 | A9601_14641 | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.427 |
hemA | hemB | A9601_08301 | A9601_02351 | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | COG113 Delta-aminolevulinic acid dehydratase [Coenzyme metabolism]; Belongs to the ALAD family. | 0.864 |
hemA | hemC | A9601_08301 | A9601_05521 | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. | 0.985 |
hemA | hemD | A9601_08301 | A9601_01311 | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Putative uroporphyrinogen III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.855 |