node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
cysG | hemA | A9601_19041 | A9601_08301 | Putative uroporphyrin-III C-methyltransferase; COG7 Uroporphyrinogen-III methylase [Coenzyme metabolism]; Belongs to the precorrin methyltransferase family. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.621 |
cysG | hemB | A9601_19041 | A9601_02351 | Putative uroporphyrin-III C-methyltransferase; COG7 Uroporphyrinogen-III methylase [Coenzyme metabolism]; Belongs to the precorrin methyltransferase family. | COG113 Delta-aminolevulinic acid dehydratase [Coenzyme metabolism]; Belongs to the ALAD family. | 0.737 |
cysG | hemC | A9601_19041 | A9601_05521 | Putative uroporphyrin-III C-methyltransferase; COG7 Uroporphyrinogen-III methylase [Coenzyme metabolism]; Belongs to the precorrin methyltransferase family. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. | 0.976 |
cysG | hemD | A9601_19041 | A9601_01311 | Putative uroporphyrin-III C-methyltransferase; COG7 Uroporphyrinogen-III methylase [Coenzyme metabolism]; Belongs to the precorrin methyltransferase family. | Putative uroporphyrinogen III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.995 |
cysG | hemE | A9601_19041 | A9601_06391 | Putative uroporphyrin-III C-methyltransferase; COG7 Uroporphyrinogen-III methylase [Coenzyme metabolism]; Belongs to the precorrin methyltransferase family. | Uroporphyrinogen decarboxylase (URO-D); Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.934 |
cysG | hemL | A9601_19041 | A9601_05391 | Putative uroporphyrin-III C-methyltransferase; COG7 Uroporphyrinogen-III methylase [Coenzyme metabolism]; Belongs to the precorrin methyltransferase family. | COG1 Glutamate-1-semialdehyde aminotransferase [Coenzyme metabolism]; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily. | 0.512 |
glgC | glpX | A9601_08311 | A9601_08291 | COG448 ADP-glucose pyrophosphorylase [Carbohydrate transport and metabolism]; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. | Fructose-1,6-bisphosphatase/sedoheptulose-1, 7-bis phosphatase; Catalyzes the hydrolysis of fructose 1,6-bisphosphate (Fru 1,6-P2) and sedoheptulose 1,7-bisphosphate (Sed 1,7-P2) to fructose 6- phosphate and sedoheptulose 7-phosphate, respectively; Belongs to the FBPase class 2 family. | 0.641 |
glgC | hemA | A9601_08311 | A9601_08301 | COG448 ADP-glucose pyrophosphorylase [Carbohydrate transport and metabolism]; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.620 |
glgC | rpe | A9601_08311 | A9601_08281 | COG448 ADP-glucose pyrophosphorylase [Carbohydrate transport and metabolism]; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. | COG36 Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Belongs to the ribulose-phosphate 3-epimerase family. | 0.535 |
glpX | glgC | A9601_08291 | A9601_08311 | Fructose-1,6-bisphosphatase/sedoheptulose-1, 7-bis phosphatase; Catalyzes the hydrolysis of fructose 1,6-bisphosphate (Fru 1,6-P2) and sedoheptulose 1,7-bisphosphate (Sed 1,7-P2) to fructose 6- phosphate and sedoheptulose 7-phosphate, respectively; Belongs to the FBPase class 2 family. | COG448 ADP-glucose pyrophosphorylase [Carbohydrate transport and metabolism]; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. | 0.641 |
glpX | hemA | A9601_08291 | A9601_08301 | Fructose-1,6-bisphosphatase/sedoheptulose-1, 7-bis phosphatase; Catalyzes the hydrolysis of fructose 1,6-bisphosphate (Fru 1,6-P2) and sedoheptulose 1,7-bisphosphate (Sed 1,7-P2) to fructose 6- phosphate and sedoheptulose 7-phosphate, respectively; Belongs to the FBPase class 2 family. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.774 |
glpX | rpe | A9601_08291 | A9601_08281 | Fructose-1,6-bisphosphatase/sedoheptulose-1, 7-bis phosphatase; Catalyzes the hydrolysis of fructose 1,6-bisphosphate (Fru 1,6-P2) and sedoheptulose 1,7-bisphosphate (Sed 1,7-P2) to fructose 6- phosphate and sedoheptulose 7-phosphate, respectively; Belongs to the FBPase class 2 family. | COG36 Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Belongs to the ribulose-phosphate 3-epimerase family. | 0.723 |
gltX | hemA | A9601_05281 | A9601_08301 | Glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.935 |
gltX | hemB | A9601_05281 | A9601_02351 | Glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | COG113 Delta-aminolevulinic acid dehydratase [Coenzyme metabolism]; Belongs to the ALAD family. | 0.454 |
hemA | cysG | A9601_08301 | A9601_19041 | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Putative uroporphyrin-III C-methyltransferase; COG7 Uroporphyrinogen-III methylase [Coenzyme metabolism]; Belongs to the precorrin methyltransferase family. | 0.621 |
hemA | glgC | A9601_08301 | A9601_08311 | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | COG448 ADP-glucose pyrophosphorylase [Carbohydrate transport and metabolism]; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. | 0.620 |
hemA | glpX | A9601_08301 | A9601_08291 | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Fructose-1,6-bisphosphatase/sedoheptulose-1, 7-bis phosphatase; Catalyzes the hydrolysis of fructose 1,6-bisphosphate (Fru 1,6-P2) and sedoheptulose 1,7-bisphosphate (Sed 1,7-P2) to fructose 6- phosphate and sedoheptulose 7-phosphate, respectively; Belongs to the FBPase class 2 family. | 0.774 |
hemA | gltX | A9601_08301 | A9601_05281 | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | 0.935 |
hemA | hemB | A9601_08301 | A9601_02351 | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | COG113 Delta-aminolevulinic acid dehydratase [Coenzyme metabolism]; Belongs to the ALAD family. | 0.864 |
hemA | hemC | A9601_08301 | A9601_05521 | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. | 0.985 |