node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
purB | purD | A9601_16671 | A9601_15411 | Fumarate lyase:Adenylosuccinate lyase; COG15 Adenylosuccinate lyase [Nucleotide transport and metabolism]; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylglycinamide synthetase; COG151 Phosphoribosylamine-glycine ligase [Nucleotide transport and metabolism]; Belongs to the GARS family. | 0.928 |
purB | purE | A9601_16671 | A9601_01851 | Fumarate lyase:Adenylosuccinate lyase; COG15 Adenylosuccinate lyase [Nucleotide transport and metabolism]; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylaminoimidazole carboxylase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.955 |
purB | purF | A9601_16671 | A9601_00031 | Fumarate lyase:Adenylosuccinate lyase; COG15 Adenylosuccinate lyase [Nucleotide transport and metabolism]; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Glutamine amidotransferase class-II:Phosphoribosyl transferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.964 |
purB | purH | A9601_16671 | A9601_02881 | Fumarate lyase:Adenylosuccinate lyase; COG15 Adenylosuccinate lyase [Nucleotide transport and metabolism]; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | AICARFT/IMPCHase bienzyme:Methylglyoxal synthase-like domain-containing protein; COG138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) [Nucleotide transport and metabolism]. | 0.992 |
purB | purK | A9601_16671 | A9601_07381 | Fumarate lyase:Adenylosuccinate lyase; COG15 Adenylosuccinate lyase [Nucleotide transport and metabolism]; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylaminoimidazole carboxylase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR); Belongs to the PurK/PurT family. | 0.956 |
purB | purL | A9601_16671 | A9601_00021 | Fumarate lyase:Adenylosuccinate lyase; COG15 Adenylosuccinate lyase [Nucleotide transport and metabolism]; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylformylglycinamidine synthetase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assis [...] | 0.909 |
purB | purM | A9601_16671 | A9601_17981 | Fumarate lyase:Adenylosuccinate lyase; COG15 Adenylosuccinate lyase [Nucleotide transport and metabolism]; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosyl formylglycinamidine cyclo-ligase; COG150 Phosphoribosylaminoimidazole (AIR) synthetase [Nucleotide transport and metabolism]. | 0.910 |
purB | purN | A9601_16671 | A9601_09701 | Fumarate lyase:Adenylosuccinate lyase; COG15 Adenylosuccinate lyase [Nucleotide transport and metabolism]; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.905 |
purB | purQ | A9601_16671 | A9601_08431 | Fumarate lyase:Adenylosuccinate lyase; COG15 Adenylosuccinate lyase [Nucleotide transport and metabolism]; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] | 0.895 |
purB | purS | A9601_16671 | A9601_08421 | Fumarate lyase:Adenylosuccinate lyase; COG15 Adenylosuccinate lyase [Nucleotide transport and metabolism]; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylformylglycinamidine synthetase PurS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to ass [...] | 0.880 |
purD | purB | A9601_15411 | A9601_16671 | Phosphoribosylglycinamide synthetase; COG151 Phosphoribosylamine-glycine ligase [Nucleotide transport and metabolism]; Belongs to the GARS family. | Fumarate lyase:Adenylosuccinate lyase; COG15 Adenylosuccinate lyase [Nucleotide transport and metabolism]; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.928 |
purD | purE | A9601_15411 | A9601_01851 | Phosphoribosylglycinamide synthetase; COG151 Phosphoribosylamine-glycine ligase [Nucleotide transport and metabolism]; Belongs to the GARS family. | Phosphoribosylaminoimidazole carboxylase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.997 |
purD | purF | A9601_15411 | A9601_00031 | Phosphoribosylglycinamide synthetase; COG151 Phosphoribosylamine-glycine ligase [Nucleotide transport and metabolism]; Belongs to the GARS family. | Glutamine amidotransferase class-II:Phosphoribosyl transferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.997 |
purD | purH | A9601_15411 | A9601_02881 | Phosphoribosylglycinamide synthetase; COG151 Phosphoribosylamine-glycine ligase [Nucleotide transport and metabolism]; Belongs to the GARS family. | AICARFT/IMPCHase bienzyme:Methylglyoxal synthase-like domain-containing protein; COG138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) [Nucleotide transport and metabolism]. | 0.976 |
purD | purK | A9601_15411 | A9601_07381 | Phosphoribosylglycinamide synthetase; COG151 Phosphoribosylamine-glycine ligase [Nucleotide transport and metabolism]; Belongs to the GARS family. | Phosphoribosylaminoimidazole carboxylase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR); Belongs to the PurK/PurT family. | 0.952 |
purD | purL | A9601_15411 | A9601_00021 | Phosphoribosylglycinamide synthetase; COG151 Phosphoribosylamine-glycine ligase [Nucleotide transport and metabolism]; Belongs to the GARS family. | Phosphoribosylformylglycinamidine synthetase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assis [...] | 0.959 |
purD | purM | A9601_15411 | A9601_17981 | Phosphoribosylglycinamide synthetase; COG151 Phosphoribosylamine-glycine ligase [Nucleotide transport and metabolism]; Belongs to the GARS family. | Phosphoribosyl formylglycinamidine cyclo-ligase; COG150 Phosphoribosylaminoimidazole (AIR) synthetase [Nucleotide transport and metabolism]. | 0.998 |
purD | purN | A9601_15411 | A9601_09701 | Phosphoribosylglycinamide synthetase; COG151 Phosphoribosylamine-glycine ligase [Nucleotide transport and metabolism]; Belongs to the GARS family. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.999 |
purD | purQ | A9601_15411 | A9601_08431 | Phosphoribosylglycinamide synthetase; COG151 Phosphoribosylamine-glycine ligase [Nucleotide transport and metabolism]; Belongs to the GARS family. | Phosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] | 0.996 |
purD | purS | A9601_15411 | A9601_08421 | Phosphoribosylglycinamide synthetase; COG151 Phosphoribosylamine-glycine ligase [Nucleotide transport and metabolism]; Belongs to the GARS family. | Phosphoribosylformylglycinamidine synthetase PurS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to ass [...] | 0.916 |